Drexel was originally called Stuart City, and under the latter name was platted in 1890. The present name of Drexel was the name of a local store owner. A post office called Drexel has been in operation since 1891.
In June 2010, the Missouri Department of Natural Resources warned of a spike of 31.2 parts herbicide atrazine per billion in Drexel's public water supply. The maximum contaminant level set by the U.S. Environmental Protection Agency for long term exposure is 3 parts per billion. The Missouri Department of Health and Senior Services recommended "neither using the water for drinking nor using it to cook, wash dishes or to make ice."
Founding dates: Wikidata, Wikipedia, the U.S. post office records of Blevins & Helbock (CC0) and the Census. Homes by year built: Census ACS 2020–24. National Register of Historic Places: National Park Service (list of May 22, 2026). Old photos, postcards and papers: Wikimedia Commons, the Library of Congress and other public archives, credited on each item’s page. Maps: U.S. Geological Survey historical topographic maps (via Esri) and Sanborn fire-insurance maps (Library of Congress). History text and census tables: Wikipedia (CC BY-SA 4.0). Places that used to be: USGS Geographic Names Information System (2021). How TownRatings grades history →
From Wikipedia, Wikidata and Wikipedia for famous people, the US Post Offices dataset (Blevins & Helbock) and the USGS Geographic Names Information System. Archive images are copied here with their credits and licenses, shown on each photo’s page. Refreshed monthly.