Each edition grades its towns against each other only.
A town of 63, settled in 1893.
Daniel Boone House and Daniel Boone Hays House is on the National Register of Historic Places. Defiance has fewer than 1,000 residents, too few for fair grades; the figures below are still real.
In a town this size, neighbors are the best guide. Ask them anything.
The archive holds 11 old photos and papers going back to 2011 and 3 maps from 1948 on.
1 place on the National Register of Historic Places.
Defiance is unincorporated, so St. Charles County and regional agencies provide most services.
EPA SDWIS (Oct 9, 2026) · HIFLD + EIA-861 2025 · Census 2020 ZCTAs · NCES 2024–25 · registration: vote.gov, updated Nov 18, 2024.
Ordered by what stands out in Defiance.
In July, afternoons reach 89°; in January, nights fall to 22°, and about 14 inches of snow falls in a winter.
NOAA U.S. Climate Normals, 1991–2020
Most people who work leave Defiance to do it: just 1% work in town. The top destinations are St. Louis (9%), Washington (7%) and Wentzville (6%). The median commute is under 15 miles.
Census LEHD 2023 · ACS
On expected storm and flood damage, Defiance sits below just over three fifths of U.S. communities. Federal aid has come to Defiance households in 4 declared disasters; the latest was in 2022. 45% of the town’s expected losses from natural hazards come from inland flooding, followed by tornadoes at 14%.
FEMA disaster declarations and aid · FEMA National Risk Index · OpenFEMA
Defiance: 6.6% of adults worry about having enough food, below both the Missouri town median (15%) and the median of U.S. towns (14%). For adults here, the share who say their health is fair or poor is 16%. Only 10 of the 248 Missouri towns we compare have a higher share of adults who had a checkup this year than Defiance. Of 32 CDC measures, Defiance beats the Missouri average on 15 and trails it on 2.
| Defiance | Missouri towns | U.S. towns | |
|---|---|---|---|
| Feel lonely (CDC PLACES) | 26% | 32% | 33% |
| Frequent mental distress (CDC PLACES) | 14% | 19% | 17% |
| Food insecurity (CDC PLACES) | 6.6% | 15% | 14% |
| Yearly checkup (CDC PLACES) | 82% | 78% | 79% |
| What stands out | Defiance | MO |
|---|---|---|
| Fewer adults facing food insecurity | 6.6% | 13.7% |
| Fewer older adults who have lost all their teeth | 8.1% | 15.8% |
| More adults who have had cancer | 11.7% | 8.6% |
CDC PLACES 2025 · modeled estimates for adults · CMS · HRSA
Zillow Home Value Index · Redfin Data Center
Museums, parks, gardens and other places to visit around Defiance. Close and well known come first.
Big draw39 mi State parkCahokia
10 mi Theme parkMid America Adventure
Big draw32 mi Stadium & arenaThe Dome at America's Center
32 mi Stadium & arenaBusch Stadium
32 mi National ParkGateway Arch National Park2.2M visitors a year
39 mi LandmarkMonks MoundCahokia: Thank You (24 Millions ) views, CC BY 2.0 · Mid America Adventure: Chris Hagerman from New Port Richey, FL, US, CC BY 2.0 · The Dome at America's Center: Paul Sableman, CC BY 2.0 · Busch Stadium: Lee Ann Ratledge, CC BY 4.0 · Gateway Arch National Park: Daniel Schwen, CC BY-SA 4.0 · Monks Mound: Skubasteve834, CC BY-SA 3.0
4 within 15 miles of the center of Defiance
About 0 of every 100 Defiance residents are enrolled in college, against 6 across Missouri.
Community in St. Charles County, Missouri, U.S.
Defiance is an unincorporated community and census-designated place in Saint Charles County, Missouri, United States. As of the 2020 census, the population was 159.
From Wikipedia, licensed CC BY-SA 4.0 · facts via Wikidata (CC0)
Short answers, built from the data on this page.
Defiance has fewer than 1,000 residents, too few for fair grades; the figures below are still real.
2 notable people were born here, including Danielle Nierenberg and Oscar Fuhr.
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